Cosmetic Raw Materials
Product Introduction
The use of Tranexamic acid in cosmetics was a complete accident. A doctor in the use of tranexamic acid (tranexamic acid) treatment of subarachnoid hemorrhage patients, accidentally found that the patient's whole body turned white! Since 1979, doctors have taken the lead in studying the effect of oral tranexamic acid (tranexamic acid) on melasma. At this point, the whitening and light spot effect of transochromic acid began to attract the attention of cosmetics companies. After a lot of research, Japan's Shiseido began using transochromic acid in its whitening and lightening products around 2005. Domestic cosmetics companies then followed up, and transochromic acid began to be popular in the domestic cosmetics market, becoming an important ingredient in the whitening and lightening spot market.
Product Data Sheets
| Item | Specification | Analytical Result |
| Characteristics | white crystalline powder | white crystalline powder |
| Identification | Infrared absorption spectrophotometry(2.2.24) IR spectrum is in concordance with Tranexamic acid CRS | Consistent with the standard |
| Solubility | Easy to dissolve in the water and the glacial acetic acid, difficult to dissolve in the acetone and the ethyl alcohol | Consistent with the standard |
| PH | 7.0—8.0 | 7.3 |
| Chloride | ≤140ppm | <140ppm |
| Sulfated ash | ≤0.1% | 0.01% |
| Heavy Metals | ≤10ppm | <10ppm |
| Loss on drying | ≤0.5% | 0.10% |
| Related substances（HPLC） | Impuriy A : ≤ 0.1% | 0.05% |
| Impuriy B: ≤ 0.2% | 0.01% | |
| Any other impuriy: ≤ 0.1% | 0.02% | |
| All other impuriy : ≤ 0.2% | 0.04% | |
| Content | 99.0%——101.0% | 99.80% |
| Conclusion | Conforms QB/LGB17C10-2 | |
tranexamic acid in cosmetic
Tranexamic acid is a protein inhibitor that can inhibit the catalytic effect of protein on bond hydrolysis, thereby preventing the activity of inflammatory proteins, and further inhibiting the disorder of epidermal cell function in the dark spots, and inhibiting the melanin enhancement factor group, and then completely cutting off the path of melanin formation due to ultraviolet radiation. That is, dark spots will no longer become thicker, larger, or more, thus effectively preventing and improving skin pigmentation.
At the same time, tranexamic acid is a patented whitening ingredient in skin care products. Years of clinical research have confirmed that tranexamic acid can quickly whiten and lighten spots, making the skin white, soft, bright and crystal clear, and it is also extremely safe.
"Tranexamic acid" first attracted people's attention because the body became white after oral administration. Oral tranexamic acid has been confirmed by a large number of studies to treat chloasma. In many beauty salons and medical beauty hospitals, the whitening injections for whitening and lightening contain tranexamic acid (tranexamic acid).
Use of tranexamic acid
The more clear indication of tranexamic acid in dermatology is chloasma, and there are three ways of administration: oral, injection, and topical.
1.Oral
For patients who are ineffective with topical hydroquinone or triple cream alone, tranexamic acid can be taken orally, or during the active period of chloasma, oral tranexamic acid can be chosen before phototherapy, and phototherapy can be performed after the stabilization period.
Many patients are worried about the adverse reactions of oral drugs. In fact, oral tranexamic acid has good overall safety and a low incidence of adverse reactions (common adverse reactions include gastrointestinal reactions, irregular menstruation, etc.). It can be used under the guidance of a professional doctor.
2.Injection
Mesotherapy is often used, which is what we often call water light injection. Transamic acid or compound low molecular weight hyaluronic acid is used for water light injection to improve chloasma.Compared with oral administration, injection can avoid systemic drug effects.
3.Topical
There are creams, smears, wet compresses, etc., which are a feasible alternative for patients who cannot tolerate oral tranexamic acid or are willing to use topical forms.
Usually, the treatment of melasma often adopts a combination of treatment methods, such as tranexamic acid combined with laser, which is better than using laser alone or tranexamic acid alone.
Contact US
To purchase tranexamic acid powder, please contact Xi'an sost biotech Factory.
Email:ericyang@xasost.com
Email:ericyang@xasost.com
Product Data Sheets
| Item | Specification | Analytical Result |
| Characteristics | white crystalline powder | white crystalline powder |
| Identification | Infrared absorption spectrophotometry(2.2.24) IR spectrum is in concordance with Tranexamic acid CRS | Consistent with the standard |
| Solubility | Easy to dissolve in the water and the glacial acetic acid, difficult to dissolve in the acetone and the ethyl alcohol | Consistent with the standard |
| PH | 7.0—8.0 | 7.3 |
| Chloride | ≤140ppm | <140ppm |
| Sulfated ash | ≤0.1% | 0.01% |
| Heavy Metals | ≤10ppm | <10ppm |
| Loss on drying | ≤0.5% | 0.10% |
| Related substances（HPLC） | Impuriy A : ≤ 0.1% | 0.05% |
| Impuriy B: ≤ 0.2% | 0.01% | |
| Any other impuriy: ≤ 0.1% | 0.02% | |
| All other impuriy : ≤ 0.2% | 0.04% | |
| Content | 99.0%——101.0% | 99.80% |
| Conclusion | Conforms QB/LGB17C10-2 | |
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