‌Theanine Powder

1. Neurocognitive Enhancement
Theanine (γ-ethylamino-L-glutamic acid) crosses the blood-brain barrier to modulate alpha brain waves (8–13 Hz), promoting relaxation without sedation. Clinical trials demonstrate that 200–400 mg/day improves focus when combined with caffeine (ratio 2:1), while reducing caffeine-induced jitters. Its dual action on glutamate/GABA pathways enhances executive function in ADHD populations.

2. Mental Health Therapeutics
As a natural anxiolytic, theanine inhibits glutamate overstimulation at NMDA receptors, alleviating stress-related disorders. A 6-week study on schizophrenia patients (400 mg/day) showed significant anxiety reduction (p<0.05) without drowsiness. Emerging evidence suggests synergistic effects with antidepressants by normalizing serotonin/dopamine levels in juvenile depression models.

3. Oncology Adjunct Therapy
Theanine potentiates chemotherapy efficacy by inhibiting tumor glutathione synthesis. In vitro, it enhances doxorubicin cytotoxicity 3.2-fold against breast cancer cells (IC50 reduction from 1.8 μM to 0.56 μM). Human trials note improved quality of life in ovarian cancer patients consuming ≥1g green tea extract daily.

4. Metabolic and Cardiovascular Support
Chronic intake (250 mg/day) reduces systolic BP by 5–7 mmHg via nitric oxide modulation. Animal studies reveal lipid-lowering effects through PPAR-α activation, decreasing LDL-C by 18%.

5. Agricultural and Industrial Uses
As a feed additive (0.1–0.3% wt), theanine improves livestock growth rates by 12% through gut microbiota modulation. In food industry, it serves as umami flavor enhancer (threshold: 0.015%) and shelf-life extender for lipid-rich products.