Active Pharmaceutical Ingredients
What is scutellaria baicalensis root extract?
Scutellaria baicalensis root extract is a mixture of active ingredients extracted from the root of the Lamiaceae plant Scutellaria baicalensis. Its core components are flavonoids (such as baicalin and baicalein), which account for over 50% of the extract. These compounds act like "little guardians," endowing Scutellaria baicalensis root extract with multiple benefits, including antibacterial, anti-inflammatory, and antioxidant properties.
Extraction Process: Dried Scutellaria baicalensis root is crushed, soaked in ethanol or water, and subjected to reflux extraction. After concentration and purification, a pale yellow powder is obtained. This powder is readily soluble in hot water but poorly soluble in cold water and oils. Therefore, it is often formulated into aqueous solutions or incorporated into cosmetics.
Historical Background: Scutellaria baicalensis has been used as a traditional Chinese medicine for over 2,000 years. Ancient people used it to treat ailments such as fever, cough, and diarrhea. Modern research has revealed that Scutellaria baicalensis root extract not only retains its traditional benefits but also demonstrates new value in areas such as skincare and antiviral treatments.
Extraction Process: Dried Scutellaria baicalensis root is crushed, soaked in ethanol or water, and subjected to reflux extraction. After concentration and purification, a pale yellow powder is obtained. This powder is readily soluble in hot water but poorly soluble in cold water and oils. Therefore, it is often formulated into aqueous solutions or incorporated into cosmetics.
Historical Background: Scutellaria baicalensis has been used as a traditional Chinese medicine for over 2,000 years. Ancient people used it to treat ailments such as fever, cough, and diarrhea. Modern research has revealed that Scutellaria baicalensis root extract not only retains its traditional benefits but also demonstrates new value in areas such as skincare and antiviral treatments.
COA
| Analysis | Description | Test Method |
| Appearance | Yellow Powder | Visual |
| Odor | Characteristic | Nasil |
| Identification | Conform with reference sample | HPLC |
| Mesh Size | 100% pass 80 mesh | CP2020 |
| Moisture Content | ≤5.0% | GB5009.3 |
| Ash Content | ≤5.0% | GB5009.4 |
| Heavy Metals | ≤ 10 ppm | CP2020 |
| Arsenic (As) | ≤ 2.0 ppm | CP2020 |
| Lead (Pb) | ≤ 2.0 ppm | CP2020 |
| Cadmium (Cd) | ≤ 1.0 ppm | CP2020 |
| Mercury (Hg) | ≤ 0.1ppm | CP2020 |
| Total Plate Count | ≤ 1,000 cfu/g | CP2020 |
| Yeast and Mold | ≤ 100 cfu/g | CP2020 |
| Escherichia Coli | Absent | CP2020 |
| Salmonella/25g | Absent | CP2020 |
| Assay(Baicalin) | ≥ 80% | HPLC |
Is Scutellaria baicalensis root extract safe for skin?
Safety Summary: Scutellaria baicalensis root extract has a risk factor of 1 (out of 10) in cosmetics, making it a low-risk ingredient. However, suitability should be determined based on skin type and intended use.
Scutellaria baicalensis root extract benefits for skin
Anti-allergy "fire extinguisher": Baicalin can inhibit hyaluronidase (an enzyme that triggers allergies), reducing redness, swelling, and itching. For example, people with sensitive skin may experience less redness after using a cream containing Scutellaria baicalensis extract.
Sunscreen "invisible shield": Baicalin and baicalein absorb UV rays (190-400nm) (covering both UVA and UVB), effectively adding a natural sunscreen to the skin. Studies have found that adding Scutellaria baicalensis extract to sunscreen can increase the SPF value by 20%-30%. Anti-Aging "Repairer": Flavonoids can scavenge free radicals (the main cause of skin aging) and inhibit elastase (an enzyme that destroys skin elasticity), reducing wrinkle formation. Long-term use of serums containing Scutellaria baicalensis extract may lead to firmer, more radiant skin.
Whitening "Blemish-Fade" Agent: Baicalein inhibits tyrosinase (a key enzyme in melanin production), reducing the formation of dark spots. Studies have shown that continuous use of whitening products containing Scutellaria baicalensis extract for three months can reduce the size of dark spots by 15%-20%. Precautions:
High concentrations may cause irritation: Pure Scutellaria baicalensis root extract concentrations exceeding 5% may cause stinging in some people (especially on broken skin).
Allergy Risk: A very small number of people are allergic to Scutellaria baicalensis. Before use, it is recommended to test the product behind the ear or on the wrist and observe for 24 hours until no reaction occurs.
Contraindications: Avoid combining with products with high concentrations of alpha-hydroxy acids or salicylic acids, as this may increase irritation.
Scutellaria baicalensis root extract benefits for skin
Anti-allergy "fire extinguisher": Baicalin can inhibit hyaluronidase (an enzyme that triggers allergies), reducing redness, swelling, and itching. For example, people with sensitive skin may experience less redness after using a cream containing Scutellaria baicalensis extract.
Sunscreen "invisible shield": Baicalin and baicalein absorb UV rays (190-400nm) (covering both UVA and UVB), effectively adding a natural sunscreen to the skin. Studies have found that adding Scutellaria baicalensis extract to sunscreen can increase the SPF value by 20%-30%. Anti-Aging "Repairer": Flavonoids can scavenge free radicals (the main cause of skin aging) and inhibit elastase (an enzyme that destroys skin elasticity), reducing wrinkle formation. Long-term use of serums containing Scutellaria baicalensis extract may lead to firmer, more radiant skin.
Whitening "Blemish-Fade" Agent: Baicalein inhibits tyrosinase (a key enzyme in melanin production), reducing the formation of dark spots. Studies have shown that continuous use of whitening products containing Scutellaria baicalensis extract for three months can reduce the size of dark spots by 15%-20%. Precautions:
High concentrations may cause irritation: Pure Scutellaria baicalensis root extract concentrations exceeding 5% may cause stinging in some people (especially on broken skin).
Allergy Risk: A very small number of people are allergic to Scutellaria baicalensis. Before use, it is recommended to test the product behind the ear or on the wrist and observe for 24 hours until no reaction occurs.
Contraindications: Avoid combining with products with high concentrations of alpha-hydroxy acids or salicylic acids, as this may increase irritation.
What are the side effects of Scutellaria baicalensis extract?
Gastrointestinal Upset: Approximately 5% of people may experience nausea, abdominal pain, and diarrhea, especially when taken on an empty stomach. It is recommended to take after meals or choose an enteric-coated tablet.
Allergic Reactions: A rare occurrence may cause itching, redness, swelling, and difficulty breathing. A small test dose (e.g., 1/4 dose) is recommended before first use.
Drug Interactions: Scutellaria baicalensis may enhance the effects of anticoagulants (such as warfarin), increasing the risk of bleeding. It may also reduce the efficacy of antihypertensive medications (such as nifedipine). People who are taking medication should consult a doctor before use.
Allergic Reactions: A rare occurrence may cause itching, redness, swelling, and difficulty breathing. A small test dose (e.g., 1/4 dose) is recommended before first use.
Drug Interactions: Scutellaria baicalensis may enhance the effects of anticoagulants (such as warfarin), increasing the risk of bleeding. It may also reduce the efficacy of antihypertensive medications (such as nifedipine). People who are taking medication should consult a doctor before use.
How to buy scutellaria baicalensis root extract?
Buy Scutellaria baicalensis root extract - Contact SoST Biotech Factory for:
✓ Bulk discounts (MOQ 25kg)
✓ FREE 20g samples with COA
✓ OEM services/Specification Customization
Email:ericyang@xasost.com
Packing & Shipping
What We Can Do?
Product Data Sheets
| Analysis | Description | Test Method |
| Appearance | Yellow Powder | Visual |
| Odor | Characteristic | Nasil |
| Identification | Conform with reference sample | HPLC |
| Mesh Size | 100% pass 80 mesh | CP2020 |
| Moisture Content | ≤5.0% | GB5009.3 |
| Ash Content | ≤5.0% | GB5009.4 |
| Heavy Metals | ≤ 10 ppm | CP2020 |
| Arsenic (As) | ≤ 2.0 ppm | CP2020 |
| Lead (Pb) | ≤ 2.0 ppm | CP2020 |
| Cadmium (Cd) | ≤ 1.0 ppm | CP2020 |
| Mercury (Hg) | ≤ 0.1ppm | CP2020 |
| Total Plate Count | ≤ 1,000 cfu/g | CP2020 |
| Yeast and Mold | ≤ 100 cfu/g | CP2020 |
| Escherichia Coli | Absent | CP2020 |
| Salmonella/25g | Absent | CP2020 |
| Assay(Baicalin) | ≥ 80% | HPLC |