Cosmetic Raw Materials
Sost Biotech Co.,ltd
Email: ericyang@xasost.com
Tel: +86 13165723260
Office: 18F Tower B, High-tech Modern City Building, Zhangba 5th Road, Xian, China, 710075
Potassium Methoxysalicylate (4MSK) Powder
Product Introduction
Potassium 4-methoxysalicylate, referred to as 4-MSK, is a relatively new whitening raw material, also known as potassium methoxycinnamate, which is similar to salicylic acid in structure.
4-MSK not only has the same effect of inhibiting melanin production as existing whitening active ingredients, but also has the effect of adjusting keratinocyte differentiation, which can improve the skin condition where melanin is easily deposited excessively.
4-MSK not only has the same ability as existing effective ingredients for inhibiting melanin production, but also has the function of regulating the differentiation of keratinocytes. It can improve the skin condition where melanin is prone to excessive accumulation.
This ingredient is often added to cosmetics to help improve the texture of the skin and repair the natural barrier of the skin, thereby making the skin smoother, more moisturized and healthier.
4-MSK was officially approved as a whitening ingredient by the Japanese authorities in 2003 and was officially introduced to China in 2007. The maximum allowable concentration for use is 3%.
4-MSK Specification
| Product name | Potassium 4-methoxysalicylate (4MSK) |
| Appearance | White powder |
| CAS No. | 152312-71-5 |
| Molecular Formula | C8h9ko4 |
| Molecular Weight | 208.25 |
| Purity | 99% |
| Storage | Keep in a cool, dry, dark location in a tightly sealed container or cylinder. |
| Shelf Life | 24 Months |
The cosmetic efficacy of 4-MSK POWDER
The classic application of 4MSK in the market
4-MSK + Metaraminol
If Tranmin Acid focuses on the effect, then 4-MSK's aim is to enhance the self-healing ability. The products that use this combination include Shiseido Pure White Spotless Essence, Kiehl's Radiant White Essence, Innisfree Whitening Repair Essence, etc.
4MSK not only forms the best combination with tranexamic acid, but also often works in conjunction with some antioxidant vitamin C and E components, such as 2-o-ethyl ascorbic acid, 3-ο-ethyl ascorbic acid and magnesium ascorbate phosphate, as well as some anti-inflammatory components, such as potassium glycyrrhizinate, to achieve a synergistic and enhancing effect.
SOST Biotech – Your Trusted Potassium Methoxysalicylate (4MSK) Powder Supplier
✅ Certified Quality: ISO/GMP-compliant manufacturing
✅ Custom Solutions: Tailored concentrations & formulations
✅ Bulk Pricing: Competitive rates for OEM Services
✅ Global Shipping: Doorstep delivery with full documentation
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Product Data Sheets
| Analysis | Description | Result |
| Appearance | Brown powder | Conform |
| Odor | No special taste | Nasil |
| Identification | Conform with reference sample | HPLC |
| Mesh Size | 90%Though 80 Mesh | Conform |
| Loss on drying | <5% | 0.038 |
| Ash Content | ≤5.0% | GB5009.4 |
| Ash content | <20% | 0.1903 |
| Content (hypericin) | >0.3% | 0.301%（uv） |
| Heavy metal | <10ppm | Conform |
| Pesticide residue | Do not detect | Conform |
| Total bacteria | <1000cfu/g | Conform |
| Saccharomyces mycobacteria | <100cfu/g | Conform |
| Escherichia coli. | Do not detect | Conform |
| Salmonella | Do not detect | Conform |