How to Use Kojic Acid Powder?

Kojic acid in cosmetics

1. Preliminary preparation

Check quality control: Use pharmaceutical grade kojic acid powder (at least 99% pure) to avoid impurities that may cause skin irritation.
pH adjustment: Dissolve the powder in distilled water or ethanol at 40-50°C (avoid boiling to prevent decomposition). The optimal stability pH is 4.0-6.0; citric acid or sodium hydroxide can be used to adjust the pH.

2. Preparation methods for different cosmetic products

  Oil and cream
. Emulsion preparation: Mix the oil phase (shea butter, jojoba oil) and the water phase (kojic acid solution, glycerin) separately at 70°C.
. Emulsification: Slowly add the oil phase to the water phase and homogenize at 2000 rpm for 5 minutes.
. Cooling and storage: Cool to 40°C, add denaturant (0.1% phenoxyethanol), and shake for 30 minutes. Recommended dosage: 0.5-2% (too high concentration may cause dehydration; please test on a small area of ​​skin before use).

  Essence and toner
.Solvent selection: Use 50% propylene glycol or 30% ethanol for better solubility in aqueous solutions.
.Improved stability: Add 0.1% EDTA as a chelating agent to prevent ionic contamination.
.Directions: Apply 2-3 drops daily to clean skin, avoiding the eye area.

How Kojic Acid is used in foods？

1. Food additives (approved for use in Japan)

Storage of soybeans: The addition of 0.05% kojic acid powder can prevent mold growth during storage.

Seafood: Soaking fish or shellfish in 0.1% kojic acid for 10 minutes can extend shelf life for 2-3 days.

pH should be considered: Works well in ambient conditions (pH < 5.5); for non-acidic foods, citric acid can be used for preparation.

2. Change in taste of fermented foods

For making beverages: The addition of 0.02% kojic acid during mash fermentation can help build amino acids, thus improving umami.

Making yogurt: Adding 0.01% kojic acid can improve stability and slow acidification.

A note of caution: Be sure to follow local regulations regarding food packaging; many countries continue to classify kojic acid as GRAS (generally recognized as safe) pending the results of long-term studies.

Pharmaceutical applications of kojic acid 

1. Advances in the treatment of fungal infections

Prophylaxis: Mix 1-3% Kojic Acid Cream with 2% Miconazole to treat tinea versicolore.

Mechanism of action: It interferes with ergosterol synthesis on fungal cell membrane and improves drug permeability.

2. Applications in Cancer Research (In Vitro/Animal Studies)

Test concentration: 50-200 µM in cell culture; 10-50 mg/kg intraperitoneally.

Note: Limited human clinical trials; work only under medical supervision.

Kojic Acid Powder Manufacturer

Xi'an Sost Biotech is the leading manufacturer of high purity Kojic Acid Powder, strictly following GMP and ISO 9001:2015 manufacturing standards. We have:

•Advanced fermentation technology: through deep fermentation and triple crystallization process, at least 99.5% choline is achieved.

•Customized solutions: provided small customized products (80-200 meshes) and packaging (1 kg to 20 kg drums) to cosmetic, food and pharmaceutical customers.

•On order: COA, MSDS and Halal/Kosher certificate available upon request.

Whether you need R&D prototypes or large scale manufacturing processes, our technical team can provide comprehensive pharmaceutical development and safety documentation support. Contact us today at ericyang@xasost.com to discuss your specific needs and receive a competitive quote.