Can ursolic acid be used as a cosmetic ingredient?

Is Ursolic Acid powder Safe to Use?

"Natural" does not mean "unscented." The "Product Use" currently lists Ursolic Acid (INCI: Ursolic Acid) as 07260, with typical concentration levels: maximum 0.5% for personal care and 0.06% for eye care. The home use assessment report shows that at these levels, nine toxicity parameters were not significantly affected, including acute oral/oral toxicity, skin sensitization, and photosensitivity, and no contaminants such as heavy metals and dioxins were present. In other words, as long as the formula stays below the above levels and exceeds the nine levels, it can be sold commercially without further restrictions.

Are the benefits of muscle regeneration and anti-aging just "hypothesis" or is it science?

The action of ursolic acid powder is based on three mechanisms:

Tyrosinase inhibition: In vitro studies have shown that ursolic acid interacts with copper ions in the active site of tyrosinase, whose IC15 was only 0.38 mM and the inhibitory effect was 3.4 times that of β-arbutin.

Antioxidant activity: With an ORAC value of 20,100 μ mol/g, trolox can scavenge UVB-induced ROS, reduce MDA by 42%, and increase SOD activity by 1.8 times.

Collagen maintenance and proliferation: A concentration of 0.1% inhibited MMP-1 expression by 35% and induced type I collagen synthesis by 28%, resulting in the dual effects of "damage prevention and regeneration".

How stable is the formula?

Ursolic acid is a pentacyclic triterpenoid weak acid with high lipid solubility and poor water solubility. It easily oxidizes and discolors at high temperatures, a pitfall for many engineers. Currently, there are four proven solutions in the industry:

Nanocrystalline encapsulation: Particle size 200–400 nm, residual content >98% after 6 months at room temperature;

Cyclodextrin inclusion: Water solubility increased 18-fold, transparency <50 NTU, suitable for water-based serums;

Liposome microencapsulation: No conflicts when combined with 3% niacinamide and 1% tranexamic acid, no separation after 8 weeks at 45°C;

Derivative upgrade: Benzyl ursolate has been listed as catalog number 07261, with a residual limit of 0.09%, improved oil solubility, and near-zero irritation.

What can i buy ursolic acid powder?

If you're looking for cosmetic ingredients, SOST Biotech's ursolic acid powder is worth adding to your shopping cart. We use supercritical CO₂-directed rosemary extraction, with HPLC purity starting at 98%, and are pesticide- and plasticizer-free. Please send us a private message or email for inquiries and free samples.