Can Fisetin Be Anti-Aging?

Fisetin, also known as Fisetin and fisetone, named because it was first extracted from a type of lacquer tree, is a flavonoid found in many trees and plants, as well as in a variety of fruits and vegetables such as strawberries, grapes, apples, persimmons, onions, and cucumbers, where fisetin's content ranges from 2 to 160 μg/g. Previous studies have proved that laccasein has good effects in antioxidant, anti-inflammatory, anti-apoptosis and neuroprotection.

Uncovering the anti-aging effects of Fisetin

a) Delaying senescent cell activity
Senescent cells are dysfunctional cells that resist apoptosis and secrete harmful pro-inflammatory factors (senescence-associated secretory phenotype, SASP). Fisetin acts as a senescence cataboliser to selectively eliminate these cells. Fisetin reduces the burden on senescent cells, prolongs life span and improves health.

b) Antioxidant and anti-inflammatory effects
Fisetin enhances cellular antioxidant capacity by activating free radicals. It also inhibits pro-inflammatory pathways such as NF-κB, reducing chronic inflammation associated with age-related diseases.

c) Fisetin can reduce cellular senescence
Studies have shown that fisetin activates the proteins SIRT1 and AMPK, which have been linked to longevity. these pathways enhance cellular repair, improving mitochondrial function and removing damaged cellular components as a key process.

Product application of Fisetin Powder

1. ProHealth Longevity

Each capsule contains 125mg of Novusetin® Lacertin extract from the Japanese fruit wax tree, which also includes Quercetin to support and maintain brain health.

 2、GenuinePurity

Each serving contains 150mg of lacinin extract to provide antioxidant support for cognitive health, heart health, and overall health. The supplement also uses liposome encapsulation technology to enhance absorption. 

3. vitalityPRO

Each serving of this supplement contains 100mg of lacinin. It is also suitable for vegans and contains no GMOs, artificial colors, preservatives, flavors or major allergens. 

4. Double Wood Supplements

Each serving contains 100mg of Lacin, a potent antioxidant that promotes free radical scavenging. This product is also suitable for vegetarians and is soy-free, gluten-free, non-GMO and vegan to meet a wide range of dietary needs.

Factory Supply Fisetin Powder 98%

As interest in fisetin grows, sourcing high-purity, bioavailable fisetin is critical for research and product development. Xi'an Sost Biotech specializes in producing premium fisetin powder (≥98% purity) using state-of-the-art extraction and purification technologies.

Contact us at ericyang@xasost.com to request samples or discuss bulk orders.

Fisetin's dual role as a senolytic and antioxidant makes it a standout candidate in anti-aging research. For institutions and manufacturers seeking reliable fisetin, Xi'an Sost Biotech delivers excellence in quality and innovation.

1. Yousefzadeh, M. J., et al. (2018). Nature Medicine, 24(8), 1246–1256. [Fisetin as a senolytic].

2. Maher, P. (2017). Journals of Gerontology, 72(4), 420–426. [Cognitive benefits in mice].

3. Zhu, Y., et al. (2020). Aging Cell, 19(10), e13222. [Physical endurance study].