Can blue-copper peptide be used as a cosmetic?

Blue copper peptideis a complex formed by the combination of tripeptide-1 (glycine-Histidine-lysine) with copper ions. Research data show that copper in the animal organism exerts important antioxidant effects in different ways, mainly through the effect of copper on the antioxidant enzymes of the organism. Copper ions are required for a number of important enzymes in the human body and skin that play a role in connective tissue formation, antioxidant protection, and cellular respiration. Copper ions also perform signaling functions that can influence cell behavior and metabolism. For example, sufficiently high levels of copper ions signal stem cell proliferation and tissue repair.

In the field of cosmetic skin care, peptides are used in human cells to regulate their activity, but the inability to reach the deeper layers of the skin to exert their efficacy is an obstacle to the current application because most peptides cannot pass through the skin's stratum corneum. Some studies have demonstrated that blue copper peptides are able to pass through the lipid barrier of the stratum corneum and reach the epidermal cells. The blue copper peptide complex is the only peptide-copper complex that can penetrate the stratum corneum.

Mechanism of action

1、Repair the functional structure of the basement membrane, promote the vitality of damaged cells
2、Repair glycosaminoglycans GAGs, restore the function of extracellular matrix
3、Promote the synthesis of collagen (I/IV/VI) and fibronectin.
4、Both anti-inflammatory and antioxidant effects

Blue copper peptide acts on the skin

Blue Copper Peptide in Skin Remodeling

Balances the breakdown of extracellular matrix proteins (ECM proteins), preventing excessive skin damage. The addition of core proteoglycans, which function by regulating the assembly of collagen fibers, prevents the formation of scars and reduces the levels of transforming growth factor (TGF-beta), which can increase scarring. Blue Copper Peptide also allows immune cells and endothelial cells to reach the site of injury, which validates the role of Blue Copper Peptide in promoting wound healing.

Stimulates Collagen Synthesis

Tripeptide-1 has been shown to stimulate the synthesis of collagen, selective glycosaminoglycans and small proteoglycan deglycosylation proteins. In addition, it regulates the synthesis of metalloproteinases, some of which exacerbate extracellular matrix proteolysis, and some of which inhibit protease activity. This suggests that blue copper peptides have a regulatory effect on protein levels in the skin.

Promotes Cellular Stem Cell Regeneration

Peptide maintains the stem cell activity of basal keratinocytes and restores their proliferative potential. The ability of Blue Copper Peptide to restore the proliferative potential of epidermal stem cells makes it a powerful player in skin repair and rejuvenation.

How to identify high quality blue copper peptide powder?

1. Appearance and color: the color of high-quality blue copper peptide crystals should be pure blue. This is because the blue copper peptide contains copper ions and its aqueous solution is blue in color. If the color of the crystals is light or uneven, it may be of lower quality or adulterated with other substances.

2. Chemical structure: The chemical structure of blue copper peptide needs to be verified by mass spectrometry to determine the molecular weight, and high performance liquid phase (HPLC) retention time comparison with standards. An accurate chemical structure is the basis for its biological activity, which can be confirmed by purchasing directly from the brand name or by testing in the laboratory.

3. Product Characteristics: Good blue copper peptide crystals are not only of high purity, but also resistant to moisture absorption and easy to store. High purity blue copper peptide crystals have clear single crystal diffraction patterns, and product purity can be proved by HPLC testing.

4. Batch production: the ability to produce large quantities is a decisive factor in ensuring the uniformity and stability of purchased product quality. Brands that are able to supply large quantities in a stable manner are usually more trustworthy.

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