Active Pharmaceutical Ingredients
What is Neohesperidin Powder?
Neohesperidin Powder is a flavonoid compound commonly found in citrus fruits such as oranges and lemons. It is a derivative of the flavonoid hesperidin, but with added methyl groups. Methyl hesperidin is often used in dietary supplements and functional foods due to its potential health benefits, including antioxidant and anti-inflammatory properties. It has also been studied for its ability to improve blood circulation, reduce inflammation, and enhance the absorption of other nutrients. Methyl hesperidin is generally considered safe for consumption, but as with any supplement, it is important to consult with a healthcare professional before use.
Product Data Sheets
| Analysis | Description | Test Method |
| Appearance | Orange yellow Powder | Visual |
| Odor | Characteristic | Nasil |
| Identification | Conform with reference sample | HPLC |
| Mesh Size | 100% pass 80 mesh | CP2020 |
| Moisture Content | ≤5.0% | GB5009.3 |
| Ash Content | ≤5.0% | GB5009.4 |
| Heavy Metals | ≤ 10 ppm | CP2020 |
| Arsenic (As) | ≤ 1.0 ppm | CP2020 |
| Lead (Pb) | ≤ 1.0 ppm | CP2020 |
| Cadmium (Cd) | ≤ 1.0 ppm | CP2020 |
| Mercury (Hg) | ≤ 0.5ppm | CP2020 |
| Total Plate Count | ≤ 1,000 cfu/g | CP2020 |
| Yeast and Mold | ≤ 100 cfu/g | CP2020 |
| Escherichia Coli | Absent | CP2020 |
| Salmonella/25g | Absent | CP2020 |
| Assay(Methyl Hesperidin) | ≥ 94% | UV |
Neohesperidin Powder benefits
Vascular protection: Neohesperidin can increase capillary stiffness and reduce permeability. It is used clinically as an adjunct therapy for the treatment of hypertension, retinal hemorrhage, and oral bleeding.
Antioxidant and anti-inflammatory: In vitro studies have shown that Neohesperidin can scavenge up to 85% of DPPH free radicals, inhibit the NF-κB pathway, and reduce the expression of inflammatory factors such as IL-6 and TNF-α.
Lipid reduction: By inhibiting HMG-CoA reductase activity, it reduces cholesterol synthesis. Four weeks of drinking Neohesperidin-rich orange juice increased HDL by 21% and reduced the LDL/HDL ratio by 16%.
Antibacterial and preservative effects: It has broad-spectrum inhibitory effects against common foodborne pathogens such as Bacillus subtilis, Salmonella, and Vibrio cholerae. In Japan and Europe, it is registered as an auxiliary ingredient in natural food preservatives (E-426).
Skin care: Neohesperidin powder in cosmetics can inhibit tyrosinase activity, lightening skin tone. It can also reduce UVB-induced erythema by providing dual photoprotection through oral and topical application.
Sports Nutrition: Recent studies have shown that supplementing with 500 mg of Neohesperidine powder daily can reduce creatine kinase (CK) and lactate dehydrogenase (LDH) levels after long-distance running and shorten recovery time.
Antioxidant and anti-inflammatory: In vitro studies have shown that Neohesperidin can scavenge up to 85% of DPPH free radicals, inhibit the NF-κB pathway, and reduce the expression of inflammatory factors such as IL-6 and TNF-α.
Lipid reduction: By inhibiting HMG-CoA reductase activity, it reduces cholesterol synthesis. Four weeks of drinking Neohesperidin-rich orange juice increased HDL by 21% and reduced the LDL/HDL ratio by 16%.
Antibacterial and preservative effects: It has broad-spectrum inhibitory effects against common foodborne pathogens such as Bacillus subtilis, Salmonella, and Vibrio cholerae. In Japan and Europe, it is registered as an auxiliary ingredient in natural food preservatives (E-426).
Skin care: Neohesperidin powder in cosmetics can inhibit tyrosinase activity, lightening skin tone. It can also reduce UVB-induced erythema by providing dual photoprotection through oral and topical application.
Sports Nutrition: Recent studies have shown that supplementing with 500 mg of Neohesperidine powder daily can reduce creatine kinase (CK) and lactate dehydrogenase (LDH) levels after long-distance running and shorten recovery time.
How to buy Neohesperidin Powder?
If you're looking for Neohesperidin powder, contact SOST Biotech, a professional plant extract manufacturer. We stock three strengths: 90%, 95%, and 98%. The minimum order quantity is 1 kg. We support third-party SGS/BV testing and offer a full range of certifications, including Halal, Kosher, and ISO 22000.
To order Neohesperidin Powder please click this link>>
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Product Data Sheets
| Analysis | Description | Test Method |
| Appearance | Orange yellow Powder | Visual |
| Odor | Characteristic | Nasil |
| Identification | Conform with reference sample | HPLC |
| Mesh Size | 100% pass 80 mesh | CP2020 |
| Moisture Content | ≤5.0% | GB5009.3 |
| Ash Content | ≤5.0% | GB5009.4 |
| Heavy Metals | ≤ 10 ppm | CP2020 |
| Arsenic (As) | ≤ 1.0 ppm | CP2020 |
| Lead (Pb) | ≤ 1.0 ppm | CP2020 |
| Cadmium (Cd) | ≤ 1.0 ppm | CP2020 |
| Mercury (Hg) | ≤ 0.5ppm | CP2020 |
| Total Plate Count | ≤ 1,000 cfu/g | CP2020 |
| Yeast and Mold | ≤ 100 cfu/g | CP2020 |
| Escherichia Coli | Absent | CP2020 |
| Salmonella/25g | Absent | CP2020 |
| Assay(Methyl Hesperidin) | ≥ 94% | UV |