Cosmetic Raw Materials
What is α-Glucosylrutin Powder?
As a cosmetic raw material, α-glucosylrutin is 12,000 times more water-soluble than rutin and has natural sunscreen and antioxidant effects. α-glucosylrutin has anti-UV, anti-blue light, free radical scavenging, antioxidant, prevention of VC raw powder discoloration, and natural pigment protection effects. α-glucosylrutin can effectively absorb ultraviolet light, inhibit the oxidation caused by ultraviolet radiation, protect the epidermis and dermis from ultraviolet damage, and prevent the formation of erythema and wrinkles. α-glucosylrutin has a strong ability to eliminate active oxygen, can inhibit lipid peroxidation, and reduce the production and deposition of pigments. It can also inhibit the production of collagenase, help maintain the skin's elasticity and firmness, prevent the oxidation and fading of pigments, and maintain the color stability of the product.
Information
| INCI Name | Glucosylrutin |
| CAS | 130603-71-3 |
| Molecular Formula | C33H40021 |
| Molecular Weight | 772.66 |
| Primary Properties | 1. Protect the epidermis and dermis from UV damage 2. Antioxidant and anti-aging |
| Product Type | Raw material |
| Production Method | Biotechnology |
| Appearance | Yellowish powder |
| Solubility | Water soluble |
| Size | Customizable |
| Application | Used in smoothing, anti-aging, and other skin care products |
| Use Recommendations | Avoid temperatures above 60°℃ |
| Use Levels | 0.05%-0.5% |
| Storage | Protected from light, heat, oxygen and moisture |
| Shelf Life | 24 months |
What is the benefit of α-Glucosylrutin Powder?
1. Dual-channel antioxidant and blue light protection
ORAC value: α-GR 10,900 μmol TE/g, 3.6 times that of vitamin C and 2.1 times that of rutin;
Blue light (450 nm)-induced ROS inhibition test: 0.05% α-GR reduced ROS in HFF-1 cells by 62%, significantly superior to the blank control;
Lipid peroxidation inhibition: 2% cream used for 28 days reduced sebum MDA content by 35%, potentially helping to correct "screen face" symptoms.
2. UV protection and color protection: "Kill two birds with one stone"
In vitro UVA absorption peak: 345 nm, absorbance A > 1.0 (0.1% aqueous solution). α-Glucosylrutin Powder can serve as a natural sunscreen booster.
Inhibition of VC discoloration: 0.2% α-Glucosylrutin reduces the color difference (ΔE) of a 10% VC serum at 45°C from 9.8 to 2.1 after 30 days, demonstrating visible color protection.
Inhibition of MMP-1/-2: qPCR testing shows that 1% α-Glucosylrutin reduces UVB-induced MMP-1 expression by 48%, slowing photoaging.
3. Skin Penetration and Bioavailability
Franz diffusion cell (0.5% aqueous solution, 24 hours): Cumulative permeation was 168 μg/cm², 12 times that of rutin.
Confocal Raman spectroscopy: α-GR showed a characteristic peak at 10 μm in the stratum corneum, demonstrating its ability to penetrate deeply into the epidermis.
After encapsulation in liposomes, permeation increased by a further 1.8 times, making it suitable for high-end anti-aging lines.
ORAC value: α-GR 10,900 μmol TE/g, 3.6 times that of vitamin C and 2.1 times that of rutin;
Blue light (450 nm)-induced ROS inhibition test: 0.05% α-GR reduced ROS in HFF-1 cells by 62%, significantly superior to the blank control;
Lipid peroxidation inhibition: 2% cream used for 28 days reduced sebum MDA content by 35%, potentially helping to correct "screen face" symptoms.
2. UV protection and color protection: "Kill two birds with one stone"
In vitro UVA absorption peak: 345 nm, absorbance A > 1.0 (0.1% aqueous solution). α-Glucosylrutin Powder can serve as a natural sunscreen booster.
Inhibition of VC discoloration: 0.2% α-Glucosylrutin reduces the color difference (ΔE) of a 10% VC serum at 45°C from 9.8 to 2.1 after 30 days, demonstrating visible color protection.
Inhibition of MMP-1/-2: qPCR testing shows that 1% α-Glucosylrutin reduces UVB-induced MMP-1 expression by 48%, slowing photoaging.
3. Skin Penetration and Bioavailability
Franz diffusion cell (0.5% aqueous solution, 24 hours): Cumulative permeation was 168 μg/cm², 12 times that of rutin.
Confocal Raman spectroscopy: α-GR showed a characteristic peak at 10 μm in the stratum corneum, demonstrating its ability to penetrate deeply into the epidermis.
After encapsulation in liposomes, permeation increased by a further 1.8 times, making it suitable for high-end anti-aging lines.
our factory is one of the main manufacturer of Rutin, we can produce rutin with purity more than 95%, for more details, please contact us.
Rutin NF11;Rutin NF11 Powder;Sophora Japonica Extract
How can i buy α-Glucosylrutin Powder?
Buy α-Glucosylrutin Powder - Contact SoST Biotech Factory for:
✓ Bulk discounts (MOQ 25kg)
✓ FREE 20g samples with COA
✓ OEM services/Specification Customization
Email:ericyang@xasost.com
Packing & Shipping
What We Can Do?
Product Data Sheets
| Analysis | Description | Test Method |
| Appearance | Yellow green powder | Visual |
| Odor | Characteristic | Organoleptic |
| Identification | Conform with reference sample | Organoleptic |
| Mesh Size | 100% pass 80 mesh | 80mesh screen |
| Moisture Content | ≤ 1.0% | GB5009.3-2016 |
| Heavy Metals | ≤ 10 ppm | GB 5009.3 |
| Arsenic (As) | ≤ 1.5 ppm | GB 5009.4 |
| Lead (Pb) | ≤ 2 ppm | GB 5009.11 |
| Cadmium（Cd） | ≤1ppm | GB 5009.12 |
| Mercury （Hg） | ≤1ppm | GB 5009.17 |
| Total Plate Count | ≤10000 cfu/g | GB 5009.15 |
| Yeast and Mold | ≤100 cfu/g | GB 5009.3 |
| Escherichia Coli | < 10cfu/g | GB 5009.4 |
| Salmonella/25g | Absent | GB 5009.11 |
| Effective constituent | Rutin≥95% | UV |