Cosmetic Raw Materials
What is α-Glucosylhesperidin Powder?
Cosmetic-grade α-glucosylhesperidin powder is a water-soluble, compliant, and highly active upgraded ingredient of "Citrus Flavonoids Plus." Its antioxidant power is approximately three times that of vitamin C, and a 0.5% concentration can increase periocular blood flow by 21% within 28 days, achieving "vascular-level" benefits by both improving dark circles and enhancing microcirculation. It also passes a -5°C antifreeze test and can act as a "natural antifreeze," making it a cost-effective, multifunctional antioxidant active in formulations for multiple scenarios, including winter outdoor use, late-night emergency care, and blue light protection.
Product Details
| Category | Content |
|---|---|
| Product Name | α-Glucosyl Hesperidin |
| Aliases | Hesperidin 3, Monoglucosyl Hesperidin |
| English Name | α-Glucosyl Hesperidin |
| Botanical Name | Hesperidin |
| Product No. | SC-017 HEALTH |
| CAS | 61713-86-6 |
| Plant Source | Pericarp and ripe fruits of citrus plants |
| Active Ingredient | Hesperidin |
| Specification | 75% |
| Product Appearance | Light yellow |
| Detection Method | HPLC |
Is α-glucosylhesperidin really an antioxidant?
1. Antioxidant – Free Radical Slayer
ORAC value: α-GH 9200 μmol TE/g, 3.1 times that of vitamin C and 1.8 times that of unchanged hesperidin;
DPPH scavenging IC50: 0.18 mg/mL, superior to the common antioxidant ferulic acid;
Blue light resistance test: 0.1% α-GH reduced 450 nm-induced ROS by 58%, significantly higher than the blank control.
2. Improve Microcirculation – "Vascular-Level" Skincare
Capillary Permeability Test: Application of a 1% α-GH gel for 7 days reduced Evans Blue exudation from the mouse ear pinna by 32%, comparable to troxerutin; Human Periocular Blood Flow: 30 subjects who used a 0.5% α-GH eye cream for 4 weeks showed a 21% increase in laser Doppler blood flow, a 12% decrease in dark circle area, and an 8% decrease in eye bag volume;
Frostbite Protection: After 30 minutes of exposure to -5°C, the time required for the skin surface temperature to return to 0°C was shortened by 40% in the α-Glucosylhesperidin Powder group, earning it the nickname "natural antifreeze."
3. Synergistic Whitening and Anti-Glycation Effects
Tyrosinase Inhibition IC50: 0.67 mg/mL, synergistic index with tranexamic acid: 1.4;
Anti-Glycation: 0.5% α-Glucosylhesperidin Powder reduced the fluorescence intensity of AGEs by 28%, supporting its "anti-sallowness" claim.
ORAC value: α-GH 9200 μmol TE/g, 3.1 times that of vitamin C and 1.8 times that of unchanged hesperidin;
DPPH scavenging IC50: 0.18 mg/mL, superior to the common antioxidant ferulic acid;
Blue light resistance test: 0.1% α-GH reduced 450 nm-induced ROS by 58%, significantly higher than the blank control.
2. Improve Microcirculation – "Vascular-Level" Skincare
Capillary Permeability Test: Application of a 1% α-GH gel for 7 days reduced Evans Blue exudation from the mouse ear pinna by 32%, comparable to troxerutin; Human Periocular Blood Flow: 30 subjects who used a 0.5% α-GH eye cream for 4 weeks showed a 21% increase in laser Doppler blood flow, a 12% decrease in dark circle area, and an 8% decrease in eye bag volume;
Frostbite Protection: After 30 minutes of exposure to -5°C, the time required for the skin surface temperature to return to 0°C was shortened by 40% in the α-Glucosylhesperidin Powder group, earning it the nickname "natural antifreeze."
3. Synergistic Whitening and Anti-Glycation Effects
Tyrosinase Inhibition IC50: 0.67 mg/mL, synergistic index with tranexamic acid: 1.4;
Anti-Glycation: 0.5% α-Glucosylhesperidin Powder reduced the fluorescence intensity of AGEs by 28%, supporting its "anti-sallowness" claim.
| Efficacy Target | Recommended Dosage |
|---|---|
| Basic Antioxidation & Color Protection | 0.1%–0.3% |
| Dark Circle Improvement & Microcirculation Enhancement | 0.5%–1% |
| High-Function Blue Light Resistance & Frostbite Protection | 1%–2% |
Where can I buy α-Glucosylhesperidin Powder?
If you are looking for food grade or α-Glucosylhesperidin Powder, please contact SOST Biotech, a professional plant extract manufacturer. The factory office is located in the high-tech zone of Xi'an. It has a GMP lab and complete HPLC and GC-MS testing laboratories.
70% / 90% HPLC cosmetic-grade α-glucosylhesperidin, tons in stock, COA, MSDS, and complete safety data sheet included.
Contact us 70% / 90% HPLC cosmetic-grade α-glucosylhesperidin, tons in stock, COA, MSDS, and complete safety data sheet included.
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