Active Pharmaceutical Ingredients
Product Introduction
Vincamine is an organic compound with the chemical formula C21H26N2O3, which is insoluble in water and is an alkaloid extracted from the rosewood plant Vincami-norL, which has been semi-synthetic and is a cerebrovascular expander. It can be used to treat cerebral arteriosclerosis, cerebral infarction and so on.
Product Data Sheets
| Items | Requirements | Results |
| Appearance | White crystalline powder,odorless | Conforms |
| Solubility | Practically insoluble in water, soluble in chloroform an methylene chloride, slightly soluble in ethanol. | Conforms |
| Melting point | 227-230℃ | 228.3-228.6℃ |
| Specific optical | +39° - +43.5°(c=1%,in pyridine) | +42.0° |
| rotation | ||
| Tests | ||
| 1) Loss on drying | ≤ 0.5% | 0.36% |
| 2) Residual on Ignition | ≤ 0.1% | 0.07% |
| 3) Solvent residual | ≤ 0.1% | Conforms |
| 4) Heavy metal | ≤ 10 ppm | Conforms |
| 5) Arsenic | ≤ 10 ppm | Conforms |
| 6) Related substance（HPLC） | Total impurities≤ 1.0% | 0.13% |
| Single impurity≤ 0.5% | 0.09% | |
| 7) Microbial limits | ||
| Colonies total | ≤ 1000 CFU/G | Conforms |
| Yeast | ≤ 100 CFU/G | Conforms |
| 8) Loose density | ≥ 0.25 g/ml | Conforms |
| Packing density | ≥ 0.50 g/ml | Conforms |
| Assay (HPLC) | 98.5%~101.5%(on dried basis) | 99.92% |
| Conclusion | This product conforms to enterprise standard |
|
Product Function
Vincamine is a drug used for stroke, ischemic hypertensive encephalopathy, cerebral arteriosclerosis, cerebral ischemia, cerebral embolism, suitable for the elimination of symptoms of progeric degeneration, such as vertigo, headache, memory loss, inattention, aphasia, Meniere's syndrome, etc. It can also be used for retinal hemorrhage, nerve tachycardia and other autonomic nerve disorders.
Product Application
It is suitable for cerebrovascular disorders, cerebral embolism, cerebral thrombosis and hemorrhage sequelae.
1.Treat psychological and behavioral disorders in the aging period, such as loss of alertness and memory, dizziness, tinnitus, time and space orientation disorders, and insomnia.
2.Acute cerebrovascular disease and post-traumatic brain syndrome.
3.Can be used to treat ischemic retinal diseases.
Packing & Shipping
What We Can Do?
Product Data Sheets
| Items | Requirements | Results |
| Appearance | White crystalline powder,odorless | Conforms |
| Solubility | Practically insoluble in water, soluble in chloroform an methylene chloride, slightly soluble in ethanol. | Conforms |
| Melting point | 227-230℃ | 228.3-228.6℃ |
| Specific optical | +39° - +43.5°(c=1%,in pyridine) | +42.0° |
| rotation | ||
| Tests | ||
| 1) Loss on drying | ≤ 0.5% | 0.36% |
| 2) Residual on Ignition | ≤ 0.1% | 0.07% |
| 3) Solvent residual | ≤ 0.1% | Conforms |
| 4) Heavy metal | ≤ 10 ppm | Conforms |
| 5) Arsenic | ≤ 10 ppm | Conforms |
| 6) Related substance（HPLC） | Total impurities≤ 1.0% | 0.13% |
| Single impurity≤ 0.5% | 0.09% | |
| 7) Microbial limits | ||
| Colonies total | ≤ 1000 CFU/G | Conforms |
| Yeast | ≤ 100 CFU/G | Conforms |
| 8) Loose density | ≥ 0.25 g/ml | Conforms |
| Packing density | ≥ 0.50 g/ml | Conforms |
| Assay (HPLC) | 98.5%~101.5%(on dried basis) | 99.92% |
| Conclusion | This product conforms to enterprise standard |
|