Active Pharmaceutical Ingredients
Indole-3-Carbinol Introduction
Indole-3-carbinol is a tumor chemopreventive substance that can be extracted from cruciferous vegetables (such as broccoli, radish and cauliflower). Indole-3-carbinol can inhibit the occurrence and development of many tumors.
Indole-3-carbinol is produced by degradation of glucosinolate brassinolate, which is widely found in cruciferous vegetables. It can inhibit the activation of NF-κB and IκBα kinases.
Source:
Indole-3-Carbinol is broken down by moss glucosulidoside.Moss glucosulidin is a species of glucoside, and sulfurin glycoside is widely existed in the plants of the family.
Foods such as west blue flowers, west blue flower seedlings, cabbage, cauliflower, and housing cabbage family can produce Indole-3-Carbinol under the action of black mustard.
Source:
Indole-3-Carbinol is broken down by moss glucosulidoside.Moss glucosulidin is a species of glucoside, and sulfurin glycoside is widely existed in the plants of the family.
Foods such as west blue flowers, west blue flower seedlings, cabbage, cauliflower, and housing cabbage family can produce Indole-3-Carbinol under the action of black mustard.
Indole-3-Carbinol Function
Indole compounds are a class of heterocyclic derivative alkaloids with significant physiological activities. The antitumor effects of this class of compounds have generally received attention.
Indole-3-Carbinol can inhibit the formation of carcinogenic DNA adducts, induce G1 phase arrest of cancer cells, arrest cell growth by inducing apoptosis, affect DNA damage repair, inhibit angiogenesis and cell metastasis and invasion, and inhibit some estrogen-dependent tumors. Indole-3-methanol has great potential for antitumor therapy.
Indole-3-Carbinol can inhibit the formation of carcinogenic DNA adducts, induce G1 phase arrest of cancer cells, arrest cell growth by inducing apoptosis, affect DNA damage repair, inhibit angiogenesis and cell metastasis and invasion, and inhibit some estrogen-dependent tumors. Indole-3-methanol has great potential for antitumor therapy.
Product Application
Used for pharmaceuticals.
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